Which of the following is NOT a use of GHB?

GHB (gamma-hydroxybutyrate) is primarily known for its use in the medical treatment of conditions like narcolepsy, where it acts as a central nervous system depressant to help manage sleep patterns. Additionally, it is sometimes considered for use in certain cases of cataplexy, a condition associated with narcolepsy.

Moreover, GHB is recognized for its potential for abuse due to its psychoactive effects and the euphoria it can induce, making it a substance monitored for misuse. Its classification encompasses both therapeutic applications and a significant potential for recreational misuse, particularly in party and club settings.

However, GHB does not have a recognized medical application for treating depression. While it might produce feelings of euphoria or relaxation, these effects do not translate to effective treatment for depressive disorders. Clinical protocols typically outline other pharmacological options that have been shown to provide therapeutic benefits for depression, such as SSRIs or SNRIs, rather than GHB. Thus, its lack of status as a treatment for depression makes this option the correct answer.