What symptom is associated with the side effects of muscarinic blockade from antipsychotic drugs?

The symptom associated with muscarinic blockade from antipsychotic drugs is dry mouth. Antipsychotic medications often have anticholinergic properties, meaning they can block the action of acetylcholine at muscarinic receptors. This blockade leads to decreased stimulation of salivary glands, resulting in reduced saliva production and consequently dry mouth, also known as xerostomia.

This effect can be particularly troubling for patients, as it may lead to difficulty swallowing, dental issues, and discomfort. Understanding the side effects related to anticholinergic activity is crucial for managing patient care and addressing these symptoms effectively.