What is the action of acetylcholinesterase inhibitors?

Prepare for the Central Nervous System Pharmacology Test with multiple-choice questions and detailed explanations. Sharpen your skills for exam success!

Acetylcholinesterase inhibitors function by inhibiting the enzyme acetylcholinesterase, which is responsible for breaking down acetylcholine in the synaptic cleft. By preventing the breakdown of acetylcholine, these inhibitors effectively increase the concentration of acetylcholine available in the synapses. This prolonged presence of acetylcholine enhances cholinergic signaling and can lead to improved function in conditions where cholinergic transmission is compromised, such as in myasthenia gravis or Alzheimer's disease.

The other options do not accurately describe the action of acetylcholinesterase inhibitors. For instance, stimulating neurotransmitter production or increasing acetylcholine synthesis involves mechanisms distinct from the inhibition of its breakdown. Blocking neurotransmitter receptors is also not relevant to the action of acetylcholinesterase inhibitors, which primarily enhance the action of acetylcholine rather than inhibit its effects at the receptor level.

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