What are the classic signs of opioid toxicity?

The classic signs of opioid toxicity include pinpoint pupils and respiratory depression. Pinpoint pupils, or miosis, are a hallmark symptom because opioids activate the parasympathetic nervous system, leading to a reduction in the size of the pupils. Respiratory depression is another critical sign of opioid toxicity, as opioids can suppress the brain's ability to regulate breathing, which can lead to inadequate oxygenation and potential respiratory failure. Recognizing these symptoms is crucial for timely intervention and management in cases of suspected opioid overdose.

In contrast to the correct answer, other options describe symptoms associated with different conditions or side effects that are not typically associated with opioid toxicity. For instance, increased heart rate and hypertension are more indicative of stimulant use or withdrawal from opioids rather than overdose. Nausea and hallucinations can occur with opioid use or withdrawal, but they are not classic signs of toxicity. Excessive sweating and agitation may arise in withdrawal scenarios or from other drug interactions, but they do not specifically point to opioid overdose. Understanding these key signs is essential for recognizing and treating opioid toxicity effectively.