What adverse effect does meperidine lack that is commonly seen with other opioids?

The correct answer identifies that meperidine, unlike most other opioids, does not typically cause miosis, which is the constriction of the pupils. Most opioids produce this effect as a result of their action on the central nervous system, leading to a consistent physiological response. However, meperidine is unique in its effects because it interacts with different receptors and has a specific metabolic pathway that results in less of this side effect.

Meperidine's primary metabolite, normeperidine, does not induce miosis effectively, which sets it apart from the classical opioid profile that commonly results in pupil constriction. This characteristic can be clinically significant as it may influence the selection of analgesics in particular patient scenarios, particularly in patients where pupil response is a valued clinical sign.

Understanding this distinction around meperidine can help in making informed decisions regarding its analgesic use and the anticipated side effects compared to other opioids. The other options, such as respiratory depression, nausea, and constipation, are all adverse effects that are commonly associated with opioid use in general and are not typically absent in the use of meperidine. Thus, they remain significant considerations when prescribing or managing a patient's pain with opioids.